Computational Foundations of Systems Biology
BME 4985/BME 6086/CSE 4095/CSE 5095
Computational Modeling/BioMEMS for Systems Biology
BME 6086/ECE 6095
Systems biology is a relatively new field, which studies complex interactions within biological systems. Computational modeling plays an important role in the study of systems biology as it can unravel complex dynamics often difficult to see intuitively. Considering the complex nature of biological systems, biological models should always be validated using relevant experiments, and BioMEMS (Biological or Biomedical MicroElectroMechanical Systems) provides an innovative platform for such experiments. BioMEMS is the science and technology of constructing devices or systems, using methods inspired from micro or nano-scale fabrication, that are used for processing, delivery, manipulation, analysis,or construction of biological and chemical entities. In this course, students will be introduced to BioMEMS with an emphasis on systems biology applications. Integrating BioMEMS with computational modeling for innovative systems biology research is interdisciplinary in nature and requires knowledge and skills for applying molecular biology, chemistry, physics, medicine, engineering, computer science, etc. Through a variety of projects, students will obtain a basic understanding of integrating BioMEMS and computational modeling for systems biology applications.